A few books and papers take a completely different tack and argue that buspirone just does the same thing SSRIs do – desensitize the presynaptic autoreceptors until the cells ignore them – and then has its antianxiety action through stimulating postsynaptic receptors. But if it’s doing the same thing as SSRIs, how come it has the opposite effect on sex drive? And how come there are some studies suggesting that it’s helpful to add buspirone onto SSRIs? Why isn’t that just doubling up on the same thing?
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